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Research Center



Steve Lacroix
2705, boulevard Laurier, RC-9800
Québec (Québec)
+1 418-654-2152
+1 418-654-2753

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The neuroscience group is organized into multidisciplinary teams that study the biological mechanisms underpinning the normal and pathological functioning of the central and peripheral nervous system and the muscular system. Researchers in this field seek to advance our understanding of physiopathology and develop new treatments for deficiencies and disabilities caused by lesions or neurological, psychiatric, and neuromuscular diseases. Research themes concern neurodegenerative, neuromuscular, and neurogenetic diseases, cerebral and spinal lesions and trauma, the regeneration and reorganization of the nervous system, mental health, ophthalmology, the development of biotherapy and standardized clinical evaluation methods, and neuromodulation treatments. Researchers are very active in Université Laval’s Regroupement Neurosciences et Santé mentale (Neurosciences and Mental Health Group).

Recent publications (see all publications in this area)

Skuk D, Tremblay JP. CD56+ Muscle Derived Cells but Not Retinal NG2+ Perivascular Cells of Nonhuman Primates are Myogenic after Intramuscular Transplantation in Immunodeficient Mice Journal of stem cell research & therapy [electronic resource],  2017. 7: 
Sudre CH, Bocchetta M, Cash D, Thomas DL, Woollacott I, Dick KM, van Swieten J, Borroni B, Galimberti D, Masellis M, Tartaglia MC, Rowe JB, Graff C, Tagliavini F, Frisoni G, Laforce R Jr, Finger E, de Mendonca A, Sorbi S, Ourselin S, Cardoso MJ, Rohrer JD, Genetic FTD Initiative, GENFI. White matter hyperintensities are seen only in GRN mutation carriers in the GENFI cohort. NeuroImage. Clinical,  2017. 15: 171-180
Skuk D, Tremblay JP. Cell Therapy in Myology: Dynamics of Muscle Precursor Cell Death after Intramuscular Administration in Non-human Primates. Molecular therapy. Methods & clinical development,  2017. Epub
Metz LM, Li DKB, Traboulsee AL, Duquette P, Eliasziw M, Cerchiaro G, Greenfield J, Riddehough A, Yeung M, Kremenchutzky M, Vorobeychik G, Freedman MS, Bhan V, Blevins G, Marriott JJ, Grand'Maison F, Lee L, Thibault M, Hill MD, Yong VW, Minocycline in MS Study Team. Trial of Minocycline in a Clinically Isolated Syndrome of Multiple Sclerosis. The New England journal of medicine,  2017. 376: 2122-2133
Laforce R Jr, Sellami L, Bergeron D, Paradis A, Verret L, Fortin MP, Houde M, Roy M, Poulin S, Macoir J, Hudon C, Bouchard RW. Validation of the Depistage Cognitif de Quebec: A New Cognitive Screening Tool for Atypical Dementias. Archives of clinical neuropsychology : the official journal of the National Academy of Neuropsychologists,  2017. Epub
Jackson S, ElAli A, Virgintino D, Gilbert MR. Blood-brain barrier pericyte importance in malignant gliomas: what we can learn from stroke and Alzheimer's disease. Neuro-oncology,  2017. Epub
Beaulieu LD, Masse-Alarie H, Ribot-Ciscar E, Schneider C. Reliability of lower limb transcranial magnetic stimulation outcomes in the ipsi- and contralesional hemispheres of adults with chronic stroke. Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology,  2017. 128: 1290-1298
Chouinard-Watkins R, Vandal M, Leveille P, Pincon A, Calon F, Plourde M. Docosahexaenoic acid prevents cognitive deficits in human apolipoprotein E epsilon 4-targeted replacement mice. Neurobiology of aging,  2017. Epub
Bories C, Arsenault D, Lemire M, Tremblay C, De Koninck Y, Calon F. Transgenic autoinhibition of p21-activated kinase exacerbates synaptic impairments and fronto-dependent behavioral deficits in an animal model of Alzheimer's disease. Aging,  2017. 9: 1386-1403
Gangloff A, Calon F, Seidah NG. Can iPCSK9-induced hypocholesterolemia starve cancer cells? Journal of clinical lipidology,  2017. 11: 600-601
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