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Research Center

Wednesday 22 Nov

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Neuroscience

Director
Steve Lacroix
Deputy director
Lisa Topolnik
Address
2705, boulevard Laurier, RC-9800
Québec (Québec)
CANADA G1V 4G2
Phone
+1 418-654-2152
Fax
+1 418-654-2753
Email
neurosciences@crchuq.ulaval.ca

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All active clinical studies

The neuroscience group is organized into multidisciplinary teams that study the biological mechanisms underpinning the normal and pathological functioning of the central and peripheral nervous system and the muscular system. Researchers in this field seek to advance our understanding of physiopathology and develop new treatments for deficiencies and disabilities caused by lesions or neurological, psychiatric, and neuromuscular diseases. Research themes concern neurodegenerative, neuromuscular, and neurogenetic diseases, cerebral and spinal lesions and trauma, the regeneration and reorganization of the nervous system, mental health, ophthalmology, the development of biotherapy and standardized clinical evaluation methods, and neuromodulation treatments. Researchers are very active in Université Laval’s Regroupement Neurosciences et Santé mentale (Neurosciences and Mental Health Group).

Recent publications (see all publications in this area)

Duchene B, Iyombe-Engembe JP, Rousseau J, Tremblay JP, Ouellet DL. From gRNA Identification to the Restoration of Dystrophin Expression: A Dystrophin Gene Correction Strategy for Duchenne Muscular Dystrophy Mutations Using the CRISPR-Induced Deletion Method. Methods in molecular biology (Clifton, N.J.) ,  2018. 1687: 267-283
Thiry L, Lemieux M, Bretzner F. AGE- AND SPEED-DEPENDENT MODULATION OF LOCOMOTOR GAITS IN DSCAM2J MUTANT MICE. Journal of neurophysiology,  2017. Epub
Masse-Alarie H, Beaulieu LD, Preuss R, Schneider C. The activation of transversus abdominis muscle during rapid limb movements depends on the anticipation of postural demand rather than on respiratory reflexes. Gait & posture,  2017. Epub
David LS, Saint-Pierre M, Lamontagne-Proulx J, Cicchetti F. The effects of cysteamine in a mouse model of levodopa-induced dyskinesias. Neuroscience letters,  2017. Epub
Tenorio-Lopes L, Henry MS, Marques D, Tremblay ME, Drolet G, Bretzner F, Kinkead R. Neonatal maternal separation opposes the facilitatory effect of castration on the respiratory response to hypercapnia of the adult male rat: evidence for the involvement of the medial amygdala. Journal of neuroendocrinology,  2017. Epub
Cisbani G, Maxan A, Kordower JH, Planel E, Freeman TB, Cicchetti F. Presence of tau pathology within foetal neural allografts in patients with Huntington's and Parkinson's disease. Brain : a journal of neurology,  2017. Epub
Bouchoucha M, Béliveau É, Kleitz F, Calon F, Fortin MA. Antibody-conjugated mesoporous silica nanoparticles for brain microvessel endothelial cell targeting Journal of materials chemistry. B, Materials for biology and medicine,  2017. 37: 7721-7735
Henry MS, Gendron L, Tremblay ME, Drolet G. Enkephalins: Endogenous Analgesics with an Emerging Role in Stress Resilience. Neural plasticity,  2017. 2017: 1546125
Mavrakanas TA, Fournier MA, Clairoux S, Amiel JA, Tremblay ME, Vinh DC, Coursol C, Thirion DJG, Cantarovich M. Neutropenia in kidney and liver transplant recipients: Risk factors and outcomes. Clinical transplantation,  2017. 31: 
Masse-Alarie H, Bergin MJG, Schneider C, Schabrun S, Hodges PW. "Discrete peaks" of excitability and map overlap reveal task-specific organization of primary motor cortex for control of human forearm muscles. Human brain mapping,  2017. Epub
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