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Amélie Fradet-Turcotte

Formation
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Autres opportunités de carrière
Axe principal
Oncologie
Adresse(s)
Hôtel-Dieu de Québec
9, rue McMahon
2765
Québec (Québec)
CANADA G1R 3S3

Téléphone(s)
+1 418-525-4444, poste 16473
Télécopieur(s)
+1 418-691-5439
Courriel(s)
Amelie.Fradet-Turcotte@crchudequebec.ulaval.ca

site web : www.aftlab.ca

Équipe de recherche

Laurent Lamalice, PhD., professionnel de recherche

Andréanne Blondeau, Msc., professionnelle de recherche

Takashi Awada, étudiant en stage

 

 

Publications récentes (voir toutes les publications de ce chercheur)

Kitevski-LeBlanc J, Fradet-Turcotte A, Kukic P, Wilson MD, Portella G, Yuwen T, Panier S, Duan S, Canny MD, van Ingen H, Arrowsmith CH, Rubinstein JL, Vendruscolo M, Durocher D, Kay LE. The RNF168 paralog RNF169 defines a new class of ubiquitylated histone reader involved in the response to DNA damage. eLife,  2017. Epub
Canny MD, Moatti N, Wan LCK, Fradet-Turcotte A, Krasner D, Mateos-Gomez PA, Zimmermann M, Orthwein A, Juang YC, Zhang W, Noordermeer SM, Seclen E, Wilson MD, Vorobyov A, Munro M, Ernst A, Ng TF, Cho T, Cannon PM, Sidhu SS, Sicheri F, Durocher D. Inhibition of 53BP1 favors homology-dependent DNA repair and increases CRISPR-Cas9 genome-editing efficiency. Nature biotechnology,  2017. Epub
Krassowski M, Paczkowska M, Cullion K, Huang T, Dzneladze I, Ouellette BFF, Yamada JT, Fradet-Turcotte A, Reimand J. ActiveDriverDB: human disease mutations and genome variation in post-translational modification sites of proteins. Nucleic acids research,  2017. Epub
Fradet-Turcotte A, Sitz J, Grapton D, Orthwein A. BRCA2 functions: from DNA repair to replication fork stabilization. Endocrine-related cancer,  2016. 23: T1-T17
Jacquet K, Fradet-Turcotte A, Avvakumov N, Lambert JP, Roques C, Pandita RK, Paquet E, Herst P, Gingras AC, Pandita TK, Legube G, Doyon Y, Durocher D, Cote J. The TIP60 Complex Regulates Bivalent Chromatin Recognition by 53BP1 through Direct H4K20me Binding and H2AK15 Acetylation. Molecular cell,  2016. 62: 409-21
Wilson MD, Benlekbir S, Fradet-Turcotte A, Sherker A, Julien JP, McEwan A, Noordermeer SM, Sicheri F, Rubinstein JL, Durocher D. The structural basis of modified nucleosome recognition by 53BP1. Nature,  2016. 536: 100-3
Lehoux M, Fradet-Turcotte A, Archambault J. Methods to assess the nucleocytoplasmic shuttling of the HPV E1 helicase and its effects on cellular proliferation and induction of a DNA damage response. Methods in molecular biology (Clifton, N.J.) ,  2015. 1249: 67-80
Hart T, Chandrashekhar M, Aregger M, Steinhart Z, Brown KR, MacLeod G, Mis M, Zimmermann M, Fradet-Turcotte A, Sun S, Mero P, Dirks P, Sidhu S, Roth FP, Rissland OS, Durocher D, Angers S, Moffat J. High-Resolution CRISPR Screens Reveal Fitness Genes and Genotype-Specific Cancer Liabilities. Cell,  2015. 163: 1515-26
Gagnon D, Fradet-Turcotte A, Archambault J. A quantitative and high-throughput assay of human papillomavirus DNA replication. Methods in molecular biology (Clifton, N.J.) ,  2015. 1249: 305-16
Orthwein A, Fradet-Turcotte A, Noordermeer SM, Canny MD, Brun CM, Strecker J, Escribano-Diaz C, Durocher D. Mitosis inhibits DNA double-strand break repair to guard against telomere fusions. Science,  2014. 344: 189-93
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