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Sheng-Xiang Lin

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Endocrinologie et néphrologie
Centre Hospitalier de l'Université Laval (CHUL)
2705, boulevard Laurier
Québec (Québec)

+1 418-525-4444, poste 46377
+1 418-654-2298

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Publications récentes (voir toutes les publications de ce chercheur)

Wang XQ, Aka JA, Li T, Xu D, Doillon CJ, Lin SX. Inhibition of 17beta-hydroxysteroid dehydrogenase type 7 modulates breast cancer protein profile and enhances apoptosis by down-regulating GRP78. The Journal of steroid biochemistry and molecular biology,  2017. 172: 188-197
Aka JA, Calvo EL, Lin SX. Estradiol-independent modulation of breast cancer transcript profile by 17beta-hydroxysteroid dehydrogenase type 1. Molecular and cellular endocrinology,  2017. 439: 175-186
Han H, Theriault JF, Chen G, Lin SX. Substrate inhibition of 17beta-HSD1 in living cells and regulation of 17beta-HSD7 by 17beta-HSD1 knockdown. The Journal of steroid biochemistry and molecular biology,  2017. 172: 36-45
Stephen P, Lin SX. RNA-dependent RNA polymerase: Addressing Zika outbreak by a phylogeny-based drug target study. Chemical biology & drug design,  2017. Epub
Xu D, Aka JA, Wang R, Lin SX. 17beta-hydroxysteroid dehydrogenase type 5 is negatively correlated to apoptosis inhibitor GRP78 and tumor-secreted protein PGK1, and modulates breast cancer cell viability and proliferation. The Journal of steroid biochemistry and molecular biology,  2017. 171: 270-280
Maltais R, Trottier A, Barbeau X, Lague P, Perreault M, Theriault JF, Lin SX, Poirier D. Impact of structural modifications at positions 13, 16 and 17 of 16beta-(m-carbamoylbenzyl)-estradiol on 17beta-hydroxysteroid dehydrogenase type 1 inhibition and estrogenic activity. The Journal of steroid biochemistry and molecular biology,  2016. 161: 24-35
Zhang B, Hu XJ, Wang XQ, Theriault JF, Zhu DW, Shang P, Labrie F, Lin SX. Human 3alpha-hydroxysteroid dehydrogenase type 3: structural clues of 5alpha-DHT reverse binding and enzyme down-regulation decreasing MCF7 cell growth. The Biochemical journal,  2016. 473: 1037-46
Aka JA, Calvo EL, Lin SX. Genomic data on breast cancer transcript profile modulation by 17beta-hydroxysteroid dehydrogenase type 1 and 17-beta-estradiol. Data in brief,  2016. 9: 1000-1012
Xu D, Lin SX. Mimicking postmenopausal steroid metabolism in breast cancer cell culture: Differences in response to DHEA or other steroids as hormone sources. The Journal of steroid biochemistry and molecular biology,  2016. 161: 92-100
He W, Gauri M, Li T, Wang R, Lin SX. Current knowledge of the multifunctional 17beta-hydroxysteroid dehydrogenase type 1 (HSD17B1). Gene,  2016. 588: 54-61
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